New disease being tested for by Embark Veterinary DNA

 

Copper Toxicosis (Accumulating) is a new test designed by Embark Veterinary in May 2024.

Since this time, many people testing dogs with Embark Veterinary (purebred and mixed alike) are coming back with their dogs being 'carriers' (not 'affected'). Understandably, owners are confused as it not something that is known to be specific to their dog's breed/s.

 

The risk of Copper Toxicosis (Accumulating) variant in breeds other than the Labrador and Doberman is currently unknown. While this variant has been studied in dogs of other breeds, the risk remains unclear.

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For dogs tested prior to May 2024, their results would not include this new test and may also come back as carrying this variant. The only way to be sure is to pay for another kit and have the dog re-tested.

 

Embark's advice 12 June 2024: "We do not recommend breeding decisions are based on this result alone at this time. We recommend considering other factors such as temperament, structure and other health testing results, when deciding whether to breed. As an added precaution, selecting a mate that has no copies of the variant would be prudent." 

 

Copper is a trace element that is essential for life, but in excess amounts it can be toxic. The liver is mainly responsible for copper metabolism and excretion, but this system can become overwhelmed by large amounts of copper. This may come from a primary genetic defect or, increased copper intake or a combination. Symptoms can range from a mild and non-specific (such as reduced appetite and vomiting) to liver dysfunction (where we see yellowing of the skin and eyes, neurologic effects, or fluid build-up in the belly). A definitive diagnosis is made through a biopsy of the liver.

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Link to Embark's website about the variant

 

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